Managing Arthritis in Midlife: What Every Woman Over 40 Should Know

a woman holding her hands with arthritis pain.

Joint pain isn’t just something that comes with “old age.” For many women, the onset of arthritis—or a worsening of existing joint discomfort—can begin much earlier than expected. In fact, midlife is one of the most common times for women to start experiencing arthritis symptoms, especially as hormonal changes associated with perimenopause and menopause begin to take hold.

At Ms.Medicine, we specialize in comprehensive care for women navigating midlife health concerns, including arthritis. From joint-friendly movement strategies to pain relief and inflammation control, we believe women deserve informed, proactive support—not dismissal or outdated assumptions. This Arthritis Awareness Month, we’re highlighting what you need to know about managing arthritis in your 40s, 50s, and beyond.

The Overlap Between Menopause and Joint Pain

Hormonal shifts during midlife influence far more than reproductive health. Estrogen plays a critical role in maintaining joint and bone health, and as estrogen levels decline during perimenopause and menopause, many women begin to notice joint stiffness, swelling, or pain—particularly in the hands, knees, hips, neck, and lower back.

This can be confusing and frustrating. Women who’ve never had a history of joint problems may wake up with stiff fingers or find that workouts now leave them more achy than energized. Others may experience a flare of symptoms that had previously been mild.

Some of the most common complaints include:

  • Morning stiffness that lasts more than 30 minutes

  • Joint pain that worsens after inactivity or overuse

  • Swelling or tenderness around the joints

  • Clicking, grinding, or limited range of motion

  • Fatigue or low-grade inflammation

While these symptoms can be linked to several different types of arthritis, osteoarthritis is the most common form to appear or worsen during midlife.

Understanding the Types of Arthritis in Women Over 40

The term “arthritis” refers to a range of conditions that cause joint inflammation and pain. The two most common types seen in women during midlife are:

1. Osteoarthritis (OA)

Often called “wear-and-tear arthritis,” OA occurs when cartilage—the protective tissue at the ends of bones—breaks down over time. This leads to pain, stiffness, and reduced mobility. Estrogen loss may accelerate this process, making OA more common in postmenopausal women.

2. Rheumatoid Arthritis (RA)

RA is an autoimmune condition that causes the body to mistakenly attack the joints. It’s more common in women and often begins between ages 30–60. Hormonal changes during menopause can sometimes trigger or worsen RA symptoms.

In both cases, early diagnosis and comprehensive management can dramatically improve function and quality of life.

What to Do If You're Experiencing Joint Pain

If you’re noticing persistent or worsening joint pain, it’s important to take it seriously—especially if the pain is interfering with your daily life, sleep, or physical activity. Don’t assume it’s just part of aging or that you need to “push through.”

Here’s what you can do:

1. Talk to a Provider Who Specializes in Midlife Women’s Health

Not all joint pain is arthritis—but if it is, catching it early allows for better treatment. At Ms.Medicine, our clinicians listen closely to your history, perform a full physical exam, and order any necessary imaging or lab work to determine the type and extent of inflammation.

2. Get a Comprehensive Evaluation

Joint pain can be influenced by multiple factors, including weight changes, hormonal fluctuations, past injuries, autoimmune conditions, or even poor sleep and chronic stress. A full evaluation helps connect the dots so you get the right care—not just temporary relief.

3. Track Your Symptoms

Keep a log of when your pain occurs, how long it lasts, what makes it better or worse, and whether other symptoms (like fatigue, swelling, or mood changes) are present. This information can help your provider identify patterns and tailor treatment to your needs.

Managing Arthritis: What Works

Effective arthritis management is personalized, holistic, and focused on preserving your quality of life. Whether your symptoms are new or longstanding, there are a variety of strategies that can help:

Joint-Friendly Movement

Staying active is essential—but so is choosing the right kind of movement. Low-impact exercises like walking, swimming, water aerobics, Pilates, and yoga can help improve joint flexibility, reduce stiffness, and maintain strength without adding stress to vulnerable joints.

A physical therapist can help you develop a routine that supports your joints and addresses imbalances. Even small amounts of movement, done consistently, can prevent stiffness and reduce pain over time.

Anti-Inflammatory Nutrition

Food can play a big role in managing arthritis. Diets rich in omega-3 fatty acids, antioxidants, and whole, unprocessed foods may help lower systemic inflammation.

Key nutrients that support joint health include:

  • Omega-3s (found in fatty fish, walnuts, flaxseed)

  • Vitamin D and calcium (important for bone density)

  • Magnesium and turmeric (may help reduce inflammation)

Limiting sugar, highly processed foods, and excessive alcohol can also help lower inflammatory markers and ease joint pain.

Pain Relief Options

Pain management should never be one-size-fits-all. Depending on your symptoms and medical history, your provider may recommend:

  • Over-the-counter NSAIDs (such as ibuprofen or naproxen)

  • Topical creams containing menthol or capsaicin

  • Prescription anti-inflammatory medications or corticosteroid injections

  • Hormone therapy, if appropriate, to address menopause-related symptoms

  • Supplements like glucosamine or chondroitin (with professional guidance)

A concierge medicine approach allows for regular check-ins and adjustments, so your plan evolves with your needs.

Lifestyle Modifications

Stress, poor sleep, and inactivity all worsen joint pain. Creating supportive habits—like prioritizing rest, engaging in gentle daily movement, and reducing stress—can enhance your body’s ability to manage pain and inflammation.

At Ms.Medicine, we view lifestyle not as a buzzword, but as a meaningful part of medical care. Our clinicians work with you to identify what’s realistic for your life and sustainable for your health.

Moving Forward with Strength and Support

Arthritis in midlife doesn’t mean giving up the activities you love or resigning yourself to constant discomfort. With the right diagnosis, support, and care plan, it’s possible to protect your joints, manage your symptoms, and continue living an active, fulfilling life.

At Ms.Medicine, we’re here to help women over 40 take ownership of their health—by validating their experiences, providing evidence-based treatment, and walking with them through the complexities of midlife.

If you’re living with joint pain or wondering whether your symptoms might be connected to hormonal changes, you’re not alone—and there’s support available.

Schedule a meet & greet with one of our expert clinicians today and start building a personalized plan to manage arthritis and protect your joint health for the years ahead.

For more in-depth strategies, tips, and resources for managing endometriosis, download the free Ms.Medicine Endometriosis Guide today. Empower yourself with the knowledge and tools to advocate for your health and well-being. 


You Might Also Like…

Next
Next

Breathing Easier, Living Better: How Hormones Impact Asthma and Allergies in Women